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Index > Protein center > NUCB2(Gene name) > Human
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  • NUCB2 (Gene name),
  • Nucleobindin-2 (Protein name ),  NUCB2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    NUCB2(NEFA);
    Protein name:
    Nucleobindin-2;
    Alternative:
    Gastric cancer antigen Zg4;DNA-binding protein NEFA;Prepronesfatin;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Calcium-binding protein. May have a role in calcium homeostasis.
    Subcellular Location:
    Membrane Peripheral membrane protein Cytoplasm Secreted
    Protein Attributes:
    Sequence length:
    420
    Sequence:
    50:
    MRWRTILLQY | CFLLITCLLT | ALEAVPIDID | KTKVQNIHPV | ESAKIEPPDT | 
    100:
    GLYYDEYLKQ | VIDVLETDKH | FREKLQKADI | EEIKSGRLSK | ELDLVSHHVR | 
    150:
    TKLDELKRQE | VGRLRMLIKA | KLDSLQDIGM | DHQALLKQFD | HLNHLNPDKF | 
    200:
    ESTDLDMLIK | AATSDLEHYD | KTRHEEFKKY | EMMKEHERRE | YLKTLNEEKR | 
    250:
    KEEESKFEEM | KKKHENHPKV | NHPGSKDQLK | EVWEETDGLD | PNDFDPKTFF | 
    300:
    KLHDVNSDGF | LDEQELEALF | TKELEKVYDP | KNEEDDMVEM | EEERLRMREH | 
    350:
    VMSEVDTNKD | RLVTLEEFLK | ATEKKEFLEP | DSWETLDQQQ | FFTEEELKEY | 
    400:
    ENIIALQENE | LKKKADELQK | QKEELQRQHD | QLEAQKLEYH | QVIQQMEQKK | 
    420:
    LQQGIPPSGP | AGELKFEPHI | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    KEGG:
    SMR:
    MIM:
    UniGene:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human Nucleobindin-2
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    E0185r
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    ELISA Kit for Human Nucleobindin-2
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    E0185m
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    ELISA Kit for Human Nucleobindin-2
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    E0185h
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    96T
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    CLIA Kit for Human Nucleobindin-2
    Cat.:
    U0185h
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    CLIA Kit for Human Nucleobindin-2
    Cat.:
    U0185r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Nucleobindin-2
    Cat.:
    U0185m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Nucleobindin-2
    Cat.:
    P0185Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Nucleobindin-2
    Cat.:
    P0185Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Nucleobindin-2
    Cat.:
    P0185Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Nucleobindin-2
    Monoclonal Antibody for Human Nucleobindin-2
    Monoclonal Antibody for Human Nucleobindin-2
    Protein for Human Nucleobindin-2
    Protein for Human Nucleobindin-2
    Protein for Human Nucleobindin-2

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    Linearity
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    References
    1. 1.
      "Human protein NEFA, a novel DNA binding/EF-hand/leucine zipper protein. Molecular cloning and sequence analysis of the cDNA, isolation and characterization of the protein."
      Barnikol-Watanabe S. , Gross N.A. , Goetz H. , Henkel T. , Karabinos A. , Kratzin H. , Barnikol H.U. , Hilschmann N.
      Biol. Chem. Hoppe-Seyler375:497-512(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PARTIAL PROTEIN SEQUENCE;VARIANT ASN-303
      tissue: Blood.
    2. 2.
      "Assembly of a high-resolution map of the Acadian Usher syndrome region and localization of the nuclear EF-hand acidic gene."
      Deangelis M.M. , Doucet J.P. , Drury S. , Sherry S.T. , Robichaux M.B. , Den Z. , Pelias M.Z. , Ditta G.M. , Keats B.J. , Deininger P.L. , Batzer M.A.
      Biochim. Biophys. Acta1407:84-91(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT ASN-303
    3. 3.
      "Serological identification and expression analysis of gastric cancer-associated genes."
      Line A. , Stengrevics A. , Slucka Z. , Li G. , Jankevics E. , Rees R.C.
      Br. J. Cancer86:1824-1830(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY;VARIANTS ASN-303 AND GLN-402 DEL
    4. 4.
      "Troglitazone, a ligand of peroxisome proliferator-activated receptor-gamma, stabilizes NUCB2 (Nesfatin) mRNA by activating the ERK1/2 pathway: isolation and characterization of the human NUCB2 gene."
      Yamada M. , Horiguchi K. , Umezawa R. , Hashimoto K. , Satoh T. , Ozawa A. , Shibusawa N. , Monden T. , Okada S. , Shimizu H. , Mori M.
      Endocrinology151:2494-2503(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT ASN-303
    5. 5.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);VARIANTS ASN-303 AND GLN-402 DEL
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT ASN-303
    8. 8.
      "Golgi retention of human protein NEFA is mediated by its N-terminal Leu/Ile-rich region."
      Nesselhut J. , Jurgan U. , Onken E. , Gotz H. , Barnikol H.U. , Hirschfeld G. , Barnikol-Watanabe S. , Hilschmann N.
      FEBS Lett.509:469-475(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
    9. 9.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-257;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    10. 10.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-332;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] ASN-303;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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